Publications

ARTICLES that included Data from or otherwise
depended upon the North American MH Registry

• Butala, B. & Brandom, B. Muscular body build and male sex are independently associated with malignant hyperthermia susceptibility. Can J Anesth/J Can Anesth. 2017; 64: 396

• Joseph M, Theroux MC, Mooney J, Falitz S, Brandom B, Byler D. Intra-operative presentation of malignant hyperthermia (confirmed by RYR1 gene mutation, c.7522C>T; p.R2508C) leads to diagnosis of King-Denborough syndrome in a child with undiagnosed myopathy.  Anesthesia Analgesia. 2016.

• Butala BN, Kang A, Guron J, Brandom BW. Long term oral dantrolene improved muscular symptoms in a malignant hyperthermia susceptible individual. Journal of Neuromuscular Diseases. 2016; 3: 115-9.

• Werneid K, Brandom B. Survey of long-term sequelae in survivors of a malignant hyperthermia reaction. Open Journal of Anesthesiology. 2016; 6: 1-7.

• Brandom BW, Kang A, Sivak EL, Young MC. Update on dantrolene in the treatment of anesthetic induced malignant hyperthermia. SOJ Anesthesiol and Pain Manag. 2015; 2(2):1-6.

• Larach MG, Brandom BW, Allen GC, Gronert GA, Lehman EB. Malignant hyperthermia deaths related to inadequate temperature monitoring, 2007-2012: a report from the North American Malignant Hyperthermia Registry of the Malignant Hyperthermia Association of the United States. Anesth Analg 2014; 119(6): 1359-1366
• Nelson P, Litman RS. Malignant hyperthermia in children: an analysis of the North American Malignant Hyperthermia Registry. Anesth Analg 2014; 118: 369-374
• Visoiu M, Young MC, Wieland K, Brandom BW. Anesthetic drugs and onset of malignant hyperthermia. Anesth Analg 2014; 118: 388-396
• Brandom BW, Bina S, Wong CA, Wallace T, Visoiu M, Isackson PJ, Vladutiu GD, Sambuughin N, Muldoon SM. Ryanodine receptor type 1 gene variants in the malignant hyperthermia-susceptible population of the United States. Anesth Analg 2013; 116:1078-86
• Lavezzi WA, Capacchione JF, Muldoon SM, Sambuughin N, Bina S, Steele D, Brandom BW. Death in the emergency department: an unrecognized awake malignant hyperthermia-like reaction in a six-year-old. Anesth Analg 2013; 116:420-3
• Brandom BW, Larach MG, Chen MA, Young MC. Complications associated with the administration of dantrolene 1987 to 2006: a report from the North American Malignant Hyperthermia Association of the United States. Anesth Analg 2011; 112:1115-23
• Larach MG, Gronert GA, Allen GC, Brandom BW, Lehman EB. Clinical presentation, treatment, and complications of malignant hyperthermia in North America from 1987 to 2006. Anesth Analg 2010; 110:498-507
• Litman RS, Flood CD, Kaplan RF, Kim YL, Tobin JR. Postoperative malignant hyperthermia; an analysis of cases from the North American Malignant Hyperthermia Registry. Anesthesiology 2008; 109:825-9
• Larach MG, Brandom BW, Allen GC, Gronert GA, Lehman EB. Cardiac arrests and deaths associated with malignant hyperthermia in North America from 1987 to 2006. Anesthesiology 2008; 108:603-11
• Newmark JL, Voelkel M, Brandom BW, Wu J. Delayed onset of malignant hyperthermia without creatine kinase elevation in a geriatric, ryanodine receptor type 1 gene compound heterozygous patient. Anesthesiology 2007; 107(2):350-3

• Burkman JM, Posner KL, Domino KB. Analysis of the clinical variables associated with recrudescence after malignant hyperthermia reactions. Anesthesiology 2007; 106:901-6
• Fink EL, Brandom BW, Torp KD. Heat stroke in the super-sized athlete. Pediatric Emergency Care 2006; 22: 510-3
• Sambuughin N, Holley H, Muldoon S, Brandom BW, de Bantel AM, Tobin JR, Nelson TE, Goldfarb LG. Screening of the entire ryanodine receptor type 1 coding region for sequence variants associated with malignant hyperthermia susceptibility in the North American Population. Anesthesiology 2005; 102:515-521
• Sei Y, Sambuughin NN, Davis EJ, Sachs D, Cuenca B, Brandom BW, Tautz T, Rosenberg H, Nelson TE, Muldoon SM. Malignant hyperthermia in North America; Genetic screening of the three hot spots in the type I ryanodine receptor gene. Anesthesiology 2004; 101:824-830
• Muldoon SM, Deuster P, Brandom BW, Bunger R: Is there a link between malignant hyperthermia and exertional heat illness. Exercise and Sport Sciences Reviews 2004; 32:174-179
• Sei Y, Sambuughin NN, Davis EJ, Sachs D, Cuenca PB, Brandom BW, Tautz T, Rosenberg H, Nelson TE, Muldoon SM: Malignant Hyperthermia in North America: genetic screening of the three hot spots in the type I ryanodine receptor gene. Anesthesiology 2004; 101:824-830
• Sei Y, Brandom BW, Bina S, Hosio E, Gallagher KL, Wyre HW, Pudimat PA, Holman SJ, Venzon DJ, Daly JW, Muldoon SM: Patients with malignant hyperthermia demonstrate an altered calcium control mechanism in B lymphocytes. Anesthesiology 2002; 97:1052-1058
• Allen GC, Larach MG, Kunselman AR, The North American MH Registry: The sensitivity and specificity of the caffeine halothane contracture test. Anesthesiology 1998; 88:579-588
• Albrecht A, Wedel DJ, Gronert GA: Masseter muscle rigidity and non-depolarizing neuromuscular blocking agents. Mayo Clin Proc 1997; 72:329-332
• Larach MG, Rosenberg H, Gronert GA, Allen GC: Hyperkalemic cardiac arrest during anesthesia in infants and children with occult myopathies. Clin Pediatr (Phila) 1997; 36:9-16
• Antognini JF: Creatine kinase alterations after acute malignant hyperthermia episodes and common surgical procedures. Anesth Analg 1995; 81:1039-1042
• Larach MG, Localio AR, Allen GC, Denborough MA, Ellis FR, Gronert GA, Kaplan RF, Muldoon SM, Nelson TE, Ording H, et al: A clinical grading scale to predict malignant hyperthermia susceptibility. Anesthesiology 1994; 80:771-779
• Larach MG, Landis JR, Bunn JS, Diaz M, The North American MH Registry: Prediction of malignant hyperthermia susceptibility in low-risk subjects. Anesthesiology 1992; 76:16-27
• Larach MG: Standardization of the caffeine halothane muscle contracture test, North American Malignant Hyperthermia Group. Anesth Analg 1989; 69:511-515