What is the inheritance pattern of MH? Who should be tested if I am found to have a mutation?

MH is inherited in an autosomal dominant pattern. This means that children, parents and sibs of an MH susceptible have a 50% chance of inheriting MH susceptibility. Aunts and uncles of the MH susceptible and grandchildren have a 25% chance. More distant relatives have a lesser chance. The decision to spend money to determine susceptibility is complex and individual and requires guidance by an expert in genetics and MH.